Cancer BiologybioRxiv
High-grade serous ovarian carcinoma organoids as models of chromosomal instability
M. Vias, L. Morrill Gavarro, C. M. Sauer…·J. D. Brenton
This study develops HGSOC patient-derived organoids to model chromosomal instability and its mutational processes, showing they represent different causes of instability and can be used for drug sensitivity testing.
DOI 10.7554/elife.83867