F. F. Fernandes

Paracoccin impacts on Paracoccidioides brasiliensis virulence and susceptibility to antifungal drugs by modifying the expression of genes related to remodeling of the yeasts cell wall

This study shows that PCN overexpression increases virulence and antifungal susceptibility in P. brasiliensis, while silencing reduces virulence and increases resistance.

Morphological aspects of immature stages of Migonemyia migonei (Diptera: Psychodidae, Phlebotominae) an important vector of Leishmaniosis in South America by scanning electron microscopy

The paper describes the immature stages of Migonemyia migonei using scanning electron microscopy, highlighting structural features and contributing to its taxonomy and phylogeny.

The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming

This paper shows that Toxoplasma gondii microneme proteins MIC1 and MIC4 bind TLR2 and TLR4 N-glycans to activate innate immune responses and regulate infection outcomes.

Galectin-3 inhibits Paracoccidioides brasiliensis growth and impacts paracoccidioidomycosis through multiple mechanisms

This study shows Galectin-3 inhibits Paracoccidioides brasiliensis growth and affects extracellular vesicle stability, suggesting a direct antimicrobial role in paracoccidioidomycosis.

Paracoccin overexpression in Paracoccidioides brasiliensis reveals the influence of chitin hydrolysis on fungal virulence and host immune response

This study overexpresses paracoccin (PCN) in Paracoccidioides brasiliensis and finds that increased PCN levels enhance chitin hydrolysis, leading to smaller chitin particles that modulate host immune responses and increase fungal virulence.