Author

C. F. Pinzan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Organism:fungi (other)· 2 Assay:proteomics· 2 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

P. A. de Castro· 3 shared G. Goldman· 2 shared T. F. dos Reis· 2 shared A. A. Brakhage· 1 shared A. Damasio· 1 shared A. F. Paes Leme· 1 shared A. H. Reis· 1 shared A. Ibrahim· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

P. A. de Castro

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 25, 2023

Deacetylation by sirtuins is important for Aspergillus fumigatus pathogenesis and virulence

N. S. Wassano, G. B. da Silva, A. H. Reis…·A. Damasio

This study shows that sirtuins in Aspergillus fumigatus are important for virulence and pathogenesis, with AfSirE deletion reducing virulence and altering protein acetylation and gene expression.

DOI 10.1101/2023.09.25.558961

fungi (other)experimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintAug 22, 2023

A phylogenetic approach to explore the Aspergillus fumigatus conidial surface-associated proteome and its role in pathogenesis

C. Valero, C. F. Pinzan, P. A. de Castro…·G. H. Goldman

The paper identifies conidial surface proteins in Aspergillus fumigatus and shows their role in immune evasion during infection.

DOI 10.1101/2023.08.22.553365

fungi (other)proteomics

𝕏 PostBluesky

MicrobiologybioRxivPreprintSep 28, 2022

A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi

T. F. dos Reis, P. A. de Castro, R. Bastos…·G. Goldman

This study identifies brilacidin as a compound that enhances the antifungal activity of caspofungin against multiple human pathogenic fungi, including overcoming resistance mechanisms.

DOI 10.1101/2022.09.28.509882

humanexperimental assay

𝕏 PostBluesky

ImmunologybioRxivJun 13, 2019

The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming

A. Sardinha-Silva, F. C. Mendonca-Natividade, C. F. Pinzan…·M. C. Roque-Barreira

This paper shows that Toxoplasma gondii microneme proteins MIC1 and MIC4 bind TLR2 and TLR4 N-glycans to activate innate immune responses and regulate infection outcomes.

DOI 10.1371/journal.ppat.1007871

mouseproteomics

𝕏 PostBluesky