Severity of SARS-CoV-2 infection as a function of the interferon landscape across the respiratory tract of COVID-19 patients.
B. Sposito, A. Broggi, L. Pandolfi, S. Crotta, R. Ferrarese, S. Sisti, N. Clementi, A. Ambrosi, E. Liu, V. Frangipane, L. Saracino, L. Marongiu, F. Facchini, A. Bottazzi, T. Fossali, , I. Zanoni
This study examines IFN-I and IFN-III expression patterns in the respiratory tract of COVID-19 patients, finding higher IFN-III levels in severe cases and varying roles across anatomical sites.
bioRxiv · Mar 30, 2021 · PreprintImmunology