E. Liu

The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability

This study identifies CD97 as a targetable vulnerability in glioblastoma through its role in tumor metabolism and signaling, supported by transcriptomic, proteomic, and functional analyses.

Suppression of epithelial proliferation and tumorigenesis by immunoglobulin A

This study shows that IgA suppresses epithelial proliferation and tumorigenesis by interacting with DMBT1, highlighting its role in maintaining mucosal homeostasis.

Discovery of a unique pathway for glutathione utilization in Francisella

This study identifies a unique GSH utilization pathway in Francisella, revealing a pseudogenized transporter gene in pathogenic strains and its role in environmental niches.

Severity of SARS-CoV-2 infection as a function of the interferon landscape across the respiratory tract of COVID-19 patients.

This study examines IFN-I and IFN-III expression patterns in the respiratory tract of COVID-19 patients, finding higher IFN-III levels in severe cases and varying roles across anatomical sites.

Inhibition of the av integrin-TGF-b axis improves natural killer cell function against glioblastoma stem cells

The paper shows that inhibiting the integrin-TGF-β axis enhances NK cell function against glioblastoma stem cells, suggesting it as a therapeutic target.

CIS checkpoint deletion enhances the fitness of cord blood derived natural killer cells transduced with a chimeric antigen receptor

This paper combines CIS checkpoint deletion with CAR engineering in NK cells to enhance their metabolic fitness and anti-tumor activity in a lymphoma model.

Reticulon and CLIMP-63 regulate nanodomain organization of peripheral ER tubules

This study shows reticulon and CLIMP-63 regulate nanodomain organization and dynamics of peripheral ER tubules through STED microscopy and live imaging.

Respiratory syncytial virus activates Rab5a to suppress IRF1-dependent IFN-{lambda} production, subverting the antiviral defense of airway epithelial cells

This paper identifies Rab5a as a host factor that RSV activates to suppress IRF1-dependent IFN-λ production, thereby reducing antiviral immunity in airway epithelial cells.

Liver physiological T1rho dynamics associated with age and gender

The paper measures liver T1rho relaxation times in women and men across different ages and menstrual phases, finding age-dependent decreases in women but not men, and no BMI association.