Author

F. Falcone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Alouffi· 2 shared J. Odegaard· 2 shared L. Le· 2 shared L. Pennington· 2 shared M. Hsieh· 2 shared R. Zee· 2 shared S. S. McDade· 2 shared T. Jardetzky· 2 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. Alouffi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

FLIP(L) determines p53 induced life or death

A. Lees, A. J. McIntyre, F. Falcone, N. T. Crawford, C. McCann, G. P. Quinn, J. Z. Roberts, T. Sessler, P. F. Gallagher, K. McAllister, K. McLaughlin, W. L. Allen, C. Holohan, L. J. Egan, A. E. Ryan, , S. S. McDade

This study identifies FLIP(L) as a p53 target that determines cell fate by promoting cell cycle arrest and inhibiting apoptosis.

bioRxiv · Nov 28, 2019 · PreprintCancer Biology

IPSE, a parasite-derived host immunomodulatory protein, is a promising therapeutic for hemorrhagic cystitis

R. Zee, E. C. Mbanefo, L. Le, L. Pennington, J. Odegaard, T. Jardetzky, A. Alouffi, J. Akinwale, F. Falcone, M. Hsieh

This paper demonstrates that H-IPSEH03, a parasite-derived protein, is effective in treating hemorrhagic cystitis by reducing bladder inflammation and promoting urothelial proliferation.

bioRxiv · Aug 25, 2018Immunology

IPSE, a urogenital parasite-derived immunomodulatory protein, ameliorates ifosfamide-induced hemorrhagic cystitis through downregulation of pro-inflammatory pathways

E. Mbanefo, L. Le, R. Zee, N. Banskota, K. Ishida, L. Pennington, J. Odegaard, T. Jardetzky, A. Alouffi, F. Falcone, M. Hsieh

This study identifies IPSE's mechanism in reducing ifosfamide-induced cystitis by downregulating pro-inflammatory pathways and oxidative stress responses in mouse bladders.

bioRxiv · Aug 3, 2018Immunology

Transcription factor activities enhance markers of drug response in cancer

L. Garcia-Alonso, F. Iorio, A. Matchan, N. Fonseca, P. Jaaks, F. Falcone, G. Bignell, S. S. McDade, M. J. Garnett, J. Saez-Rodriguez

The paper uses computational methods to infer transcription factor activities from RNA-seq data and shows their utility as markers for drug response in cancer.

bioRxiv · Apr 21, 2017Cancer Biology