BRN2 is a non-canonical melanoma tumor-suppressor
M. Hamm, P. Sohier, V. Petit, J. Raymond, V. Delmas, M. Le Coz, F. Gesbert, C. Kenny, Z. Aktary, M. Pouteaux, F. Rambow, A. Sarasin, A. Bellacosa, L. Sanchez-del-Campo, L. Mosteo, , L. Larue
This study identifies BRN2 as a non-canonical tumor suppressor in melanoma, showing its role in initiation and progression through PTEN regulation and PI3K signaling.
bioRxiv · Jan 13, 2021Cancer Biology