Author

E. Steingrimsson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

C. Kenny· 3 shared R. Cornell· 3 shared L. Larue· 2 shared A. Bellacosa· 1 shared A. Bhinu· 1 shared A. Helverson· 1 shared A. K. Arnadottir· 1 shared A. Sarasin· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

C. Kenny

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Author profile →

3 papers

Recent·Most cited

Antagonistic Roles for MITF and TFE3 in Melanoma Plasticity

J. Chang, K. R. Campbell-Hanson, M. Vanneste, N. I. Bartschat, R. Nagel, A. K. Arnadottir, H. Nhung Vu, C. Montgomery, J. Yevdash, J. Jiarui, A. Bhinu, A. Helverson, M. Henry, E. Steingrimsson, R. J. Weigel, , C. Kenny

This study identifies TFE3 and the non-canonical mTORC1 pathway as regulators of melanoma cell state plasticity, showing MITF suppresses the mesenchymal phenotype by modulating TFE3 expression.

bioRxiv · Jul 11, 2024Cancer Biology

BRN2 is a non-canonical melanoma tumor-suppressor

M. Hamm, P. Sohier, V. Petit, J. Raymond, V. Delmas, M. Le Coz, F. Gesbert, C. Kenny, Z. Aktary, M. Pouteaux, F. Rambow, A. Sarasin, A. Bellacosa, L. Sanchez-del-Campo, L. Mosteo, , L. Larue

This study identifies BRN2 as a non-canonical tumor suppressor in melanoma, showing its role in initiation and progression through PTEN regulation and PI3K signaling.

bioRxiv · Jan 13, 2021Cancer Biology

MITF reprograms the extracellular matrix and focal adhesion in melanoma

R. Dilshat, V. Fock, C. Kenny, I. Gerritsen, R. M. J. Lasseur, O. Eichhoff, J. Travnickova, P. Cerny, K. Moller, S. Sigurbjornsdottir, K. Kirty, B. O. Einarsdottir, P. F. Cheng, M. Levesque, R. Cornell, , E. Steingrimsson

This study shows MITF represses ECM and focal adhesion genes in melanoma, affecting cell morphology and matrix interactions, with reversible effects observed upon MITF knockdown.

bioRxiv · Jul 14, 2020Cancer Biology