Author

F. Jalali-Yazdi

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Biophysics· 1

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Approach:experimental assay· 1

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C. Yoshioka· 1 shared E. Gouaux· 1 shared S. Chowdhury· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperBiophysics

C. Yoshioka

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1 paper

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BiophysicsbioRxivJul 26, 2018

Mechanisms for zinc and proton inhibition of the GluN1/GluN2A NMDA receptor

F. Jalali-Yazdi, S. Chowdhury, C. Yoshioka, E. Gouaux

This study uses cryo-EM to determine the structure of the GluN1/GluN2A NMDAR under varying zinc and proton concentrations, revealing how zinc binding affects channel gating.

DOI 10.1016/j.cell.2018.10.043

experimental assay

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