Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
G. M. Martin, M. W. Sung, Z. Yang…·S.-L. Shyng
This study reveals how pharmacochaperones stabilize KATP channels by binding to SUR1 and supporting Kir6.2 N-terminus insertion, enabling mutant channel assembly.
F. Jalali-Yazdi, S. Chowdhury, C. Yoshioka, E. Gouaux
This study uses cryo-EM to determine the structure of the GluN1/GluN2A NMDAR under varying zinc and proton concentrations, revealing how zinc binding affects channel gating.
G. M. Martin, B. Kandasamy, F. DiMaio…·S.-L. Shyng
The paper presents a cryo-EM structure of KATP channels bound to glibenclamide and ATP, revealing the drug's binding site and its interaction with the channel.
G. M. Martin, C. Yoshioka, E. A. Rex…·S.-L. Shyng
The paper presents a cryo-EM structure of the KATP channel, revealing assembly and gating mechanisms involving SUR1 and Kir6.2 interactions with ATP and PIP2.