Author

F. Ke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

I. L. Grigorova· 2 shared A. Duran· 1 shared A. L. Dent· 1 shared C. Li· 1 shared D. Sun· 1 shared E. Enbody· 1 shared G. Chen· 1 shared H. Wen· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersImmunology

I. L. Grigorova

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

SARS-CoV-2 B Epitope-Guided Neoantigen NanoVaccines Enhance Tumor-Specific CD4/CD8 T Cell Immunity Through B Cell Antigen Presentation

C. Li, S. Mao, Z. Montemayor, M. D. M. Traore, A. Duran, F. Ke, M. Djibo, H. Wen, W. Gao, D. Sun

This study develops a neoantigen vaccine using SARS-CoV-2 B cell epitopes to enhance CD4/CD8 T cell immunity through B cell antigen presentation, showing improved efficacy in multiple cancer models.

bioRxiv · Jul 18, 2024Immunology

Characterization of Z chromosomal inversion and lineage-specific sweeps reveal widespread local adaptation in Helicoverpa armigera

F. Ke

The paper identifies adaptive loci and chromosomal inversions in Helicoverpa armigera lineages from China and Oceania, revealing local adaptation mechanisms and insecticide resistance genes.

bioRxiv · Sep 28, 2023 · PreprintEvolutionary Biology

Genetic basis and evolution of structural color polymorphism in an Australian songbird

S. Y. W. Sin, F. Ke, G. Chen, P.-Y. Huang, E. Enbody, J. Karubian, M. Webster, S. V. Edwards

The paper investigates the genetic basis of melanism in white-winged fairywren subspecies, finding that the mainland blue subspecies re-evolved blue plumage from a black ancestor through genetic changes in ASIP and SCUBE2.

bioRxiv · Sep 3, 2023Evolutionary Biology

Nuclear proteins acquiring Germinal Center B cells are specifically suppressed by follicular regulatory T cells.

F. Ke, Z. L. Benet, M. P. Maz, J. Liu, A. L. Dent, J. M. Kahlenberg, I. L. Grigorova

The paper shows that follicular regulatory T cells (Tfrs) suppress GC B cells acquiring nuclear proteins, indicating direct Tfr-GC B cell interactions regulate effector B cell responses.

bioRxiv · Oct 25, 2022Immunology

B cell receptor crosslinking can augment T cell help-mediated germinal center B cell selection.

J. S. Turner, F. Ke, I. L. Grigorova

This study shows that T cell help alone can drive GC B cell expansion and plasmablast formation, while BCR crosslinking synergizes with T cell help to enhance these responses when T cell help is limited.

bioRxiv · Aug 29, 2018 · PreprintImmunology