Author

F. L. Dix

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Finch· 1 shared A. Pantazi· 1 shared A. Quintanilla· 1 shared E. Parasyraki· 1 shared J. C. Acosta· 1 shared J. Patel· 1 shared N. Tarrats· 1 shared P. Hari· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Finch

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1 paper

Recent·Most cited

Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

A. Pantazi, A. Quintanilla, P. Hari, N. Tarrats, E. Parasyraki, F. L. Dix, J. Patel, T. Chandra, J. C. Acosta, A. Finch

This study shows that inhibiting LSG1, a GTPase involved in 60S ribosome biogenesis, induces cellular senescence through ER disruption and cholesterol biosynthesis upregulation, with potential therapeutic implications.

bioRxiv · Nov 8, 2018Cancer Biology