Author

F. Libert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:differential expression· 3 Organism:human· 3 Organism:mouse· 3 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Lefort· 4 shared M. Tarabichi· 3 shared C. Maenhaut· 2 shared E. Raspe· 2 shared L. Craciun· 2 shared M. Leprovots· 2 shared M.-I. Garcia· 2 shared P. P. Roger· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersCell Biology

A. Lefort

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Idiosyncratic and generic single nuclei and spatial transcriptional patterns in papillary and anaplastic thyroid cancers

A. Tourneur, J. Rodrigues Vitoria, M. Saiselet, L. Craciun, D. Larsimont, A. Lefort, F. Libert, C. Maenhaut, S. Costagliola, M. Tarabichi, M. Romitti, V. Detours

This study uses single nuclei RNA-seq and spatial transcriptomics to analyze transcriptional patterns in papillary and anaplastic thyroid cancers, revealing idiosyncratic and generic transcriptional variations and EMT-related features.

bioRxiv · Feb 15, 2024 · PreprintCancer Biology

Starvation resistant cavefish reveal conserved mechanisms of starvation-induced hepatic lipotoxicity

M. Pozo-Morales, A. E. Cobham, C. Centola, M. C. McKinney, P. Liu, C. Perazzolo, A. Lefort, F. Libert, H. Bai, N. Rohner, S. P. Singh

The paper identifies FATP2 as a conserved target for preventing starvation-induced liver atrophy by reducing fatty acid uptake in cavefish and other species.

bioRxiv · Jan 10, 2024 · PreprintCell Biology

CDK4 phosphorylation status and rational use for combining CDK4/6 and BRAF/MEK inhibition in advanced thyroid carcinomas

J. M. Pita, E. Raspe, K. Coulonval, M. Decaussin-Petrucci, M. Tarabichi, G. Dom, F. Libert, L. Craciun, G. Andry, L. Wicquart, E. Leteurtre, C. Tresallet, L. A. Marlow, J. A. Copland, C. Durante, , P. P. Roger

This study shows that CDK4 phosphorylation status predicts response to CDK4/6 inhibitors in thyroid carcinomas and supports combining them with BRAF/MEK inhibitors to prevent resistance.

bioRxiv · Jun 5, 2023Cancer Biology

THE OLFACTORY RECEPTOR Olfr78 REGULATES DIFFERENTIATION OF ENTEROCHROMAFFIN CELLS IN THE MOUSE COLON

M.-I. Garcia, G. Dinsart, M. Leprovots, A. Lefort, F. Libert, Y. Quesnel, A. Veiten, G. Vassart, S. Huysseune, M. Parmentier

This study shows that the olfactory receptor Olfr78 regulates enterochromaffin cell differentiation in the mouse colon, affecting gut homeostasis and microbiota balance.

bioRxiv · Apr 19, 2023 · PreprintCell Biology

Preclinical evaluation of CDK4 phosphorylation predicts high sensitivity of malignant pleural mesotheliomas to CDK4/6 inhibition

S. Paternot, E. Raspe, C. Meiller, M. Tarabichi, J.-B. Assie, F. Libert, M. Remmelink, X. Bisteau, P. Pauwels, Y. Blum, N. Le Stang, S. Tabone-Eglinger, F. Galateau-Salle, C. Blanquart, J. P. Van Meerbeeck, , P. P. Roger

This study shows that CDK4 phosphorylation predicts sensitivity of malignant pleural mesothelioma to CDK4/6 inhibitors, with 80% of tumors expressing phosphorylated CDK4.

bioRxiv · Apr 11, 2022Cancer Biology

COLD ATMOSPHERIC PLASMA DIFFERENTIALLY AFFECTS CELL RENEWAL AND DIFFERENTIATION OF STEM CELLS AND APC-DEFICIENT-DERIVED TUMOR CELLS IN INTESTINAL ORGANOIDS

A. Hadefi, M. Leprovots, M. Thulliez, O. Bastin, A. Lefort, F. Libert, A. Nonclercq, A. Delchambre, F. Reniers, J. Deviere, M.-I. Garcia

This study examines how cold atmospheric plasma affects stem cells and tumor cells in intestinal organoids, finding differential responses with tumor cells showing higher resistance.

bioRxiv · Oct 13, 2021Cell Biology