Spatial determination and prognostic impact of the fibroblast transcriptome in pancreatic ductal adenocarcinoma
W. Croft, H. Pearce, S. Margielewska-Davies, L. Lim, S. M. Nicol, F. Zayou, D. Blakeway, F. Marcon, S. Powell-Brett, B. Mahon, R. Merard, J. Zuo, G. Middleton, K. Roberts, R. M. Brown, P. Moss
The paper uses spatial transcriptomics and scRNA-Seq to analyze fibroblast subtypes in pancreatic ductal adenocarcinoma, linking their transcriptomes to clinical outcomes and suggesting therapeutic targets.
bioRxiv · Jan 20, 2023Cancer Biology