Author

E. L. German

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Assay:flow cytometry· 1

Frequent Co-Authors

E. Mitsi· 4 shared A. M. Collins· 3 shared C. Solorzano· 3 shared D. M. Ferreira· 3 shared E. Nikolaou· 3 shared H. Hill· 3 shared J. Reine· 3 shared S. P. Jochems· 3 shared

Activity by Year

2018-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

E. Mitsi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dynamic changes in innate immune and T cell function and composition at the nasal mucosa across the human lifespan

J. Reine, B. F. Carniel, C. Solorzano, E. Mitsi, S. Pojar, E. Nikolau, E. L. German, A. D. Hyder-Wright, H. Hill, C. Hales, L. Brown, V. Horsley, L. Hughes, S. Zaidi, V. Connor, , S. P. Jochems

This study examines age-related changes in nasal mucosal immune composition and function, finding reduced granulocytes and T cells in young children and older adults, and links pneumococcal colonization to inflammation.

bioRxiv · Mar 14, 2019 · PreprintImmunology

Minimally-invasive nasal sampling in children offers accurate pneumococcal colonization detection

E. Nikolaou, A. Blizard, S. Pojar, E. Mitsi, E. L. German, J. Reine, H. Hill, P. S. McNamara, A. M. Collins, D. M. Ferreira, S. P. Jochems

This study shows that nasal lining fluid filter strips provide equal pneumococcal detection sensitivity to deep nasopharyngeal swabs in children, offering a less unpleasant alternative.

bioRxiv · Mar 13, 2019Microbiology

Efficacy of PCV vaccine is primarily mediated by controlling pneumococcal colonisation density

E. L. German, C. Solorzano, S. Sunny, F. Dunne, J. F. Gritzfeld, E. Mitsi, E. Nikolaou, A. D. Hyder-Wright, A. M. Collins, S. B. Gordon, D. Ferreira

This study re-evaluates PCV-13 efficacy using molecular methods, finding reduced colonisation acquisition and density, suggesting vaccine impact is primarily through controlling colonisation density.

bioRxiv · Feb 14, 2019 · PreprintMicrobiology

Inflammation induced by influenza virus impairs innate control of human pneumococcal carriage

S. P. Jochems, F. Marcon, B. F. Carniel, M. Holloway, E. Mitsi, E. Smith, J. F. Gritzfeld, C. Solorzano, J. Reine, S. Pojar, E. Nikolaou, E. L. German, A. Hyder-Wright, H. Hill, C. Hales, , D. M. Ferreira

This study shows that influenza virus infection impairs innate immune responses to pneumococcal carriage in the nose, increasing bacterial density through cytokine-driven mechanisms.

bioRxiv · Jun 20, 2018Immunology