L. Lim

Viromes of Antarctic fish resembles the diversity found at lower latitudes

The paper analyzes viromes of Antarctic fish to compare viral diversity with lower latitude fish, finding comparable complexity and evidence of host-switching and viral adaptation.

Simulation-based dosimetry of transcranial and intranasal photobiomodulation of the human brain: the roles of wavelength, power density and skin colour

This study uses Monte Carlo simulations to investigate how wavelength, power density, and skin colour affect light penetration and energy accumulation in transcranial and intranasal photobiomodulation of the human brain.

Deep-Learning for Automated Markerless Tracking of Infants General Movements

This paper develops a deep-learning method for markerless tracking of infant general movements in video recordings, achieving high accuracy across multiple anatomical locations.

ATP energy-independentlymodulates the folding equilibrium of ALScausing C71G-hPFN1

This study investigates how ATP modulates the folding equilibrium of the ALS-causing C71G-hPFN1 mutant, revealing its role in inducing folding, inhibiting aggregation, and increasing stability.

Total infectome investigation of diphtheritic stomatitis in yellow-eyed penguins (Megadyptes antipodes) reveals a novel and abundant megrivirus

The paper investigates the infectome of diphtheritic stomatitis in yellow-eyed penguins, identifying a novel megrivirus associated with the disease.

Only Zn2+ and Fe2+ out of 12 cations can fold ALS-linked nascent hSOD1

This paper identifies Zn2+ and Fe2+ as the only cations among 12 tested that can induce folding of nascent hSOD1, with implications for ALS pathogenesis.

Spatial determination and prognostic impact of the fibroblast transcriptome in pancreatic ductal adenocarcinoma

The paper uses spatial transcriptomics and scRNA-Seq to analyze fibroblast subtypes in pancreatic ductal adenocarcinoma, linking their transcriptomes to clinical outcomes and suggesting therapeutic targets.

Influenza C and D viral load in cattle correlates with bovine respiratory disease (BRD): Emerging role of orthomyxoviruses in the pathogenesis of BRD

This study investigates the association between influenza C and D viral loads and bovine respiratory disease in cattle, finding higher viral loads and coinfections in BRD-symptomatic animals.

ATP induces protein folding, inhibits aggregation and antagonizes destabilization by effectively mediating water-protein-ion interactions, the heart of protein folding and aggregation

This study shows ATP induces protein folding, inhibits aggregation, and stabilizes proteins by mediating water-protein-ion interactions, with triphosphate being key but aggregation-prone, while ATP prevents this.

ATP emerged to induce protein folding, inhibit aggregation and increase stability

The paper shows ATP induces protein folding, inhibits aggregation, and increases stability by combining adenosine and triphosphate.

Spatial control of oxygen delivery to 3D cultures alters cancer cell growth and gene expression

The paper compares cancer cell growth and gene expression in different oxygen environments, finding that controlled oxygen delivery in 3D cultures better mimics physiological conditions.

TMEM106B, a risk factor for FTLD and aging, has an intrinsically disordered cytoplasmic domain

This study identifies the TMEM106B cytoplasmic domain as intrinsically disordered, enabling its dynamic and transient interactions with multiple proteins.