ImmunologybioRxivPreprint
Deep sequencing of the T cell Receptor reveals common and reproducible CD8+ signatures of response to checkpoint immunotherapy
R. A. Watson, C. Taylor, O. Tong…·B. P. Fairfax
The paper uses TCR sequencing to identify CD8+ T cell clones associated with response to checkpoint immunotherapy in metastatic melanoma, finding a correlation between peripheral ER clone proportion and clinical outcome.