Author

F. Mulero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Organism:human· 1

Frequent Co-Authors

A. C. Pena· 1 shared C. Martins· 1 shared C. Sanchez· 1 shared C. Sanz· 1 shared D. M. Rassl· 1 shared D. Macias· 1 shared D. Munoz-Espin· 1 shared D. Veroutis· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. C. Pena

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2 papers

Recent·Most cited

miR-203 drives breast cancer cell differentiation

N. G. Martinez-Illescas, S. Leal, P. Gonzalez, O. Grana, J. J. M. Oliveira, A. C. Pena, M. Q. Fandino, E. Ciruelos, C. Sanz, S. Aragon, L. Sotolongo, S. Jimenez, E. J. Caleiras, F. Mulero, C. Sanchez, , M. Salazar-Roa

This study shows that miR-203 promotes differentiation of breast cancer cells, reduces their self-renewal and growth, and suggests it as a potential therapeutic tool.

bioRxiv · Jan 23, 2023Cancer Biology

A tumour-promoting senescent secretome triggered by platinum chemotherapy exploits a targetable TGFβR1/Akt-mTOR axis in lung cancer

E. Gonzalez-Gualda, D. Macias, S. Morsli, E. Martin, H.-L. Ou, M. Denholm, I. Olan, R. Hoffmann, M. Dane, D. Veroutis, G. Medrano, F. Mulero, C. Martins, M. Barbacid, V. Gorgoulis, , D. Munoz-Espin

This study shows platinum chemotherapy induces a senescent secretome in lung cancer that promotes tumor growth via the TGFβR1/Akt-mTOR axis, and targeting this pathway reduces tumor burden.

bioRxiv · Aug 1, 2022 · PreprintCancer Biology