P. Gonzalez

Failed reprogramming of transformed cells due to induction of apoptosis and senescence impairs tumor progression in lung cancer

The paper shows that OSKM expression in lung cancer cells induces apoptosis and senescence, limiting tumor growth and reducing tumor burden in vivo.

Characterization of the bioaccumulation and toxicity of copper pyrithione, an antifouling compound, on juveniles of rainbow trout

This study compares the toxicity of copper pyrithione (CuPT) and ionic copper (Cu2+) on rainbow trout juveniles, finding CuPT more toxic with higher mortality and gene expression changes.

Robust biomarker discovery through multiplatform multiplex image analysis of breast cancer clinical cohorts

The paper identifies prognostic spatial biomarkers in breast cancer by analyzing multiple clinical cohorts using three multiplex imaging technologies.

miR-203 drives breast cancer cell differentiation

This study shows that miR-203 promotes differentiation of breast cancer cells, reduces their self-renewal and growth, and suggests it as a potential therapeutic tool.

Thermal phenotypic plasticity of pre- and post-copulatory male harm buffers sexual conflict in wild Drosophila melanogaster

This study shows that thermal phenotypic plasticity of male harm mechanisms in Drosophila melanogaster reduces the impact of sexual conflict on female fitness across different temperatures.

Antifungal activity of Cinnamomum cassia and Origanum compactum essential oils against Aspergillus oryzae

This study evaluates the antifungal activity of two essential oils against Aspergillus oryzae, finding that Origanum compactum is fungistatic and Cinnamomum cassia is both fungistatic and fungicidal.

Uptake of Fe-fraxetin complexes, an IRT1 independent strategy for iron acquisition in Arabidopsis thaliana.

This study shows that fraxetin improves iron nutrition in Arabidopsis thaliana at high pH by directly transporting Fe(III) into roots, bypassing the FRO2/IRT1 system.

Endemic and epidemic human alphavirus infections in Eastern Panama, An Analysis of Population-Based Cross-Sectional Surveys

The paper investigates endemic and epidemic alphavirus infections in eastern Panama using serosurveys and statistical modeling, finding recent increases in MADV and VEEV infections.

Systems Analysis of Subjects Acutely Infected with Chikungunya Virus

This study uses systems biology to analyze blood transcriptomes of CHIKV-infected adults, identifying gene signatures linked to viral RNA and symptoms, and comparing them to dengue and rheumatoid arthritis.