Author

F. Peccati

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Torres-Mozas· 2 shared C. D. Navo· 2 shared A. M. Woodard· 1 shared A. Rodriguez De Lera· 1 shared A. Schedlbauer· 1 shared B. Vaz· 1 shared C. Martinez· 1 shared D. A. Mitchell· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Torres-Mozas

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Synthesis and pharmacological characterization of UVI3502, a novel cannabinoid receptor 1 (CB1) antagonist/inverse agonist

I. Bengoetxea de Tena, G. Pereira-Castelo, J. Martinez-Gardeazabal, M. Moreno-Rodriguez, I. Manuel, C. Martinez, B. Vaz, J. Gonzalez-Ricarte, R. Alvarez, A. Torres-Mozas, F. Peccati, G. Jimenez Oses, A. Rodriguez De Lera, R. Rodriguez-Puertas

This paper synthesizes and characterizes UVI3502, a novel CB1 receptor antagonist/inverse agonist, showing high affinity for CB1 and low affinity for CB2, with potential interactions with GPR55.

bioRxiv · Jun 14, 2024 · PreprintPharmacology & Toxicology

Benzylic Radical Stabilization Permits Ether Formation During Darobactin Biosynthesis

A. M. Woodard, F. Peccati, C. D. Navo, G. J. Oses, D. A. Mitchell

This paper investigates how DarE enzyme modifies DarA to form ether and C-C crosslinks, identifying key residues and mechanisms involved in radical-mediated biosynthesis.

bioRxiv · Nov 29, 2023 · PreprintBiochemistry

Thermodynamic Stabilization of Human Frataxin

R. Nunez-Franco, A. Torres-Mozas, C. D. Navo, A. Schedlbauer, M. Azkargorta, I. Iloro, F. Elortza, G. Ortega, O. Millet, F. Peccati, G. Jimenez-Oses

This study thermodynamically stabilizes human frataxin using computational methods, improving its stability and resistance to proteolysis without compromising function.

bioRxiv · Sep 8, 2023 · PreprintBiophysics