Author

O. Millet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:protein structure· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:deep learning· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Escobedo· 2 shared B. Topal· 2 shared G. Ortega· 2 shared J. Aranda· 2 shared J. Garcia· 2 shared M. Orozco· 2 shared R. Crehuet· 2 shared T. Diercks· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersBiophysics

A. Escobedo

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Electrostatic Trade-Off between Mesophilic Stability and Adaptation in Halophilic Proteins

P. Herrero-Alfonso, A. Pejenaute, O. Millet, G. Ortega

This study investigates how halophilic proteins achieve stability in high salt environments by analyzing the trade-off between electrostatic interactions and thermodynamic stability.

bioRxiv · Jan 8, 2024Biophysics

Thermodynamic Stabilization of Human Frataxin

R. Nunez-Franco, A. Torres-Mozas, C. D. Navo, A. Schedlbauer, M. Azkargorta, I. Iloro, F. Elortza, G. Ortega, O. Millet, F. Peccati, G. Jimenez-Oses

This study thermodynamically stabilizes human frataxin using computational methods, improving its stability and resistance to proteolysis without compromising function.

bioRxiv · Sep 8, 2023 · PreprintBiophysics

Redox regulation of Kv7 channels through EF3 hand of calmodulin

E. Nunez, F. Jones, A. Muguruza-Montero, J. Urrutia, A. Aguado, C. Malo, C. Domene, G. Bernardo-Seisdedos, O. Millet, N. Gamper, A. Villarroel

This study shows that EF3 hand of calmodulin mediates redox regulation of Kv7 channels by translating Ca2+ signals and reversing FRET signals in response to oxidation.

eLife · Feb 20, 2023Peer-reviewedCell Biology

A glutamine-based single α-helix scaffold to target globular proteins

A. Escobedo, J. G. Piccirillo, J. Aranda, T. Diercks, B. Topal, M. Biesaga, L. Staby, B. B. Kragelund, J. Garcia, O. Millet, M. Orozco, M. Coles, R. Crehuet, X. Salvatella

This paper introduces a method to design peptides that fold into single α-helices using glutamine side chain to main chain hydrogen bonds, enabling targeted interactions with globular proteins.

bioRxiv · May 6, 2022Biophysics

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in the activation domain of a transcription factor

A. Escobedo, B. Topal, M. B. A. Kunze, J. Aranda, G. Chiesa, D. Mungianu, G. Bernardo-Seisedos, B. Eftekharzadeh, M. Gairi, R. Pieratelli, I. Felli, T. Diercks, O. Millet, J. Garcia, M. Orozco, , X. Salvatella

This study investigates how polyglutamine tract length affects the structure and function of the androgen receptor, revealing hydrogen bonds that stabilize a helical conformation linked to transcriptional activity and disease.

bioRxiv · Feb 28, 2019Biophysics