Distinct molecular signatures of fission predict mitochondrial degradation or proliferation
T. Kleele, T. Rey, J. Winter, S. Zaganelli, D. Mahecic, H. Perreten Lambert, F. Ruberto, M. Nemir, T. Wai, T. Pedrazzini, S. Manley
The paper identifies two distinct fission types in mitochondria, one leading to degradation and the other to proliferation, both Drp1-mediated but using different adaptors and pre-constriction mechanisms.
Nature · May 20, 2021Peer-reviewedCell Biology