Author

D. Mahecic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:microscopy & imaging analysis· 3 Research Focus:cell signaling & trafficking· 2 Assay:fluorescence / live-cell microscopy· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:imputation· 1

Frequent Co-Authors

S. Manley· 4 shared T. Kleele· 2 shared A. Colom· 1 shared A. Goujon· 1 shared A. Roux· 1 shared C. Zhang· 1 shared D. Fortun· 1 shared D. Gambarotto· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersCell Biology

S. Manley

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Author profile →

4 papers

Recent·Most cited

Event-driven acquisition for content-enriched microscopy

D. Mahecic, W. L. Stepp, C. Zhang, J. Griffie, M. Weigert, S. Manley

The paper introduces an event-driven acquisition framework that enhances microscopy by capturing dynamic biological events with optimized imaging rates.

bioRxiv · Oct 4, 2021Cell Biology

Distinct molecular signatures of fission predict mitochondrial degradation or proliferation

T. Kleele, T. Rey, J. Winter, S. Zaganelli, D. Mahecic, H. Perreten Lambert, F. Ruberto, M. Nemir, T. Wai, T. Pedrazzini, S. Manley

The paper identifies two distinct fission types in mitochondria, one leading to degradation and the other to proliferation, both Drp1-mediated but using different adaptors and pre-constriction mechanisms.

Nature · May 20, 2021Peer-reviewedCell Biology

Mitochondrial membrane tension governs fission

D. Mahecic, L. Carlini, T. Kleele, A. Colom, A. Goujon, S. Matile, A. Roux, S. Manley

The paper investigates mitochondrial fission dynamics, finding that membrane tension influences the likelihood of constrictions dividing.

bioRxiv · Oct 20, 2020Biophysics

Homogeneous multifocal excitation for high-throughput super-resolution imaging

D. Mahecic, D. Gambarotto, K. M. Douglass, D. Fortun, N. Banterle, M. Le Guennec, K. A. Ibrahim, P. Gonczy, V. Hamel, P. Guichard, S. Manley

This paper develops a high-throughput super-resolution imaging technique to enable large-scale, high-resolution imaging of biological structures.

Nature Methods · Jun 22, 2020Peer-reviewedBiophysics