Anti-diuretic hormone ITP signals via a guanylate cyclase receptor to modulate systemic homeostasis in Drosophila
J. Gera, M. Agard, H. Nave, A. B. Baldridge, F. Sajadi, L. Thorat, T. H. McKim, S. Kondo, D. Nassel, M. H. Omar, J.-P. V. Paluzzi, M. Zandawala
This paper characterizes the ITP signaling system in Drosophila, identifying ITPa as an anti-diuretic hormone that acts via the Gyc76C receptor to modulate osmoregulation and metabolic homeostasis.
bioRxiv · Feb 7, 2024Physiology