PhysiologyProceedings of the National Academy of SciencesPeer-reviewed
The V-type H+-ATPase is targeted in anti-diuretic hormone control of the Malpighian (renal) tubules
F. Sajadi, M. F. Vergara-Martinez, J.-P. V. Paluzzi
This paper shows that CAPA inhibits diuretic hormone-induced secretion in mosquito Malpighian tubules by reducing V-type H+-ATPase activity through NOS/cGMP/PKG signaling and promoting VA complex dissociation.
DOI 10.1073/pnas.2308602120