Chemoproteomics reveals immunogenic and tumor-associated cell surface substrates of ectokinase CK2α
C. S. Delaveris, S. Kong, J. Glasgow, R. P. Loudermilk, L. L. Kirkemo, F. Zhao, F. Salangsang, P. Phojanakong, J. A. C. Serrano, V. Steri, J. A. Wells
The paper uses chemoproteomics to identify immunogenic cell surface substrates of CK2α in the tumor microenvironment, showing that extracellular phosphorylation can generate immunogenic antigens.
bioRxiv · Mar 20, 2024Biochemistry