S. Kong

Chemoproteomics reveals immunogenic and tumor-associated cell surface substrates of ectokinase CK2α

The paper uses chemoproteomics to identify immunogenic cell surface substrates of CK2α in the tumor microenvironment, showing that extracellular phosphorylation can generate immunogenic antigens.

Single extracellular vesicle imaging and computational analysis identifiesinherent architectural heterogeneity

The paper uses cryo-TEM and a segmentation model to analyze EV architecture, finding consistent structural heterogeneity across different sources and purification methods.

Deep learning approaches to the phylogenetic placement of extinct pollen morphotypes

This paper uses deep learning to place fossil pollen specimens in a phylogeny by transforming morphological features into predicted phylogenetic distances.

A Likelihood Ratio Test for Hybridization Under the Multispecies Coalescent

This paper introduces a likelihood ratio test for detecting hybridization using genomic data under the multispecies coalescent, showing improved power over existing methods.

Inference of Phylogenetic Networks from Sequence Data using Composite Likelihood

This paper introduces PhyNEST, a method for estimating phylogenetic networks from sequence data using composite likelihood, showing improved efficiency and accuracy compared to existing methods.

Gaq-PKD/PKCμ regulates the IkB transcription to limit the NF-kB mediated inflammatory response essential for early pregnancy

This study shows that Gaq-PKD/PKCμ regulates IκB transcription to limit NF-κB-mediated inflammation, essential for successful early pregnancy.

Topological incongruence between Median-Joining Networks and Bayesian inference phylogenies

The paper compares Median-Joining Networks (MJNs) and Bayesian Inference (BI) phylogenies using 55 empirical datasets, finding significant discrepancies in branching patterns.

The Phosphate Deprivation Response is Mediated by an Interaction between Brassinosteroid Signaling and Zinc in Tomato

This study shows that brassinosteroid signaling and zinc accumulation in tomato mediate a constitutive phosphate deprivation response, offering a new strategy for plant adaptation to phosphate starvation.

Infant antibody repertoires during the first two years of influenza vaccination

This paper studies how influenza vaccination in infants shapes their antibody responses, finding that vaccination can lead to immune imprinting similar to infection, with shifts in B-cell specificity and adult-like antibody repertoires after the second year.

Spatial compartmentalization of signalling imparts source-specific functions on secreted factors

The paper identifies distinct functions of VEGFA from different cell types in skeletal muscle regeneration through time-resolved transcriptomic analysis and functional experiments.

SOX4 facilitates PGR protein stability and FOXO1 expression conducive for human endometrial decidualization

This study identifies SOX4 as a critical regulator of human endometrial decidualization by modulating PGR stability and FOXO1 expression, linking its dysregulation to infertility and pregnancy complications.

The Evolutionary History of Small RNAs in the Solanaceae

The paper uses over 255 small RNA datasets to characterize the small RNA landscape across the Solanaceae family, revealing dynamic evolutionary patterns and genus-specific similarities.

The function of macromolecular complex of CFTR-NHERF2-LPA2 in inflammatory responses of intestinal epithelial cells

This study investigates the role of the CFTR-NHERF2-LPA2 complex in inflammatory responses of intestinal epithelial cells, finding it necessary for IL-8 expression.