The bile acid receptor TGR5 is a modulator of bone marrow adipose tissue and the hematopoietic niche
A. Alonso-Calleja, A. Perino, F. Schyrr, S. Ferreira Lopes, V. Delitsikou, A. Jalil, U. Kettenberger, M. C. Galavotti, A. Martins, C. Bataclan, D. P. Pioletti, K. Schoonjans, O. Naveiras
This study shows TGR5 modulates bone marrow adipose tissue and hematopoietic niche in a sex-dependent manner, affecting progenitor reconstitution and myeloid recovery.
bioRxiv · Nov 22, 2023 · PreprintCell Biology