Boosting with ALVAC-HIV and AIDSVAX B/E enhances Env constant region 1 and 2 antibody-dependent cellular cytotoxicity
D. Easterhoff, J. Pollara, K. Luo, W. D. Tolbert, B. Young, D. Mielke, S. Jha, R. J. O'Connell, S. Vasan, J. Kim, N. Michael, J.-L. Excler, M. L. Robb, S. Rerks-Ngarm, J. Kaewkungwal, , G. Ferrari
The paper shows that boosting RV144 vaccine recipients with ALVAC-HIV and AIDSVAX B/E increases C1C2-specific antibody-dependent cellular cytotoxicity breadth and potency.
bioRxiv · May 9, 2019 · PreprintImmunology