Author

D. Easterhoff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

S. M. Alam· 3 shared B. F. Haynes· 2 shared K. O. Saunders· 2 shared A. P. Kane· 1 shared B. Watts· 1 shared B. Young· 1 shared C. Hart· 1 shared D. Mielke· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

S. M. Alam

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

B cells discriminate HIV-1 Envelope protein affinities by sensing antigen binding association rates

M. A. Hossain, K. Anasti, B. Watts, K. Cronin, A. P. Kane, R. J. Edwards, D. Easterhoff, J. Zhang, W. Rountree, Y. Ortiz, L. Verkoczy, M. Reth, S. M. Alam

This study investigates how B cells distinguish HIV-1 Env proteins based on binding kinetics rather than equilibrium dissociation constants.

bioRxiv · Jan 14, 2022 · PreprintImmunology

Boosting with ALVAC-HIV and AIDSVAX B/E enhances Env constant region 1 and 2 antibody-dependent cellular cytotoxicity

D. Easterhoff, J. Pollara, K. Luo, W. D. Tolbert, B. Young, D. Mielke, S. Jha, R. J. O'Connell, S. Vasan, J. Kim, N. Michael, J.-L. Excler, M. L. Robb, S. Rerks-Ngarm, J. Kaewkungwal, , G. Ferrari

The paper shows that boosting RV144 vaccine recipients with ALVAC-HIV and AIDSVAX B/E increases C1C2-specific antibody-dependent cellular cytotoxicity breadth and potency.

bioRxiv · May 9, 2019 · PreprintImmunology

Functional Improbable Antibody Mutations Critical for HIV Broadly Neutralizing Antibody Development

K. Wiehe, T. Bradley, R. R. Meyerhoff, C. Hart, W. Williams, D. Easterhoff, W. J. Faison, T. B. Kepler, K. O. Saunders, S. M. Alam, M. Bonsignori, B. F. Haynes

The paper identifies improbable mutations critical for HIV broadly neutralizing antibody development and proposes a mutation-guided vaccine strategy.

bioRxiv · Feb 9, 2018Immunology