Author

F. Vrieling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

R. Stienstra· 2 shared S. Kersten· 2 shared A. L. Feitsma· 1 shared B. J. Ignacio· 1 shared B. Naus· 1 shared C. Carvalho dos Santos· 1 shared C. G. Engele· 1 shared C. J. Korbee· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

R. Stienstra

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In-depth immunometabolic profiling by measuring cellular protein translation inhibition via bioorthogonal noncanonical amino acid tagging (CENCAT)

F. Vrieling, H. J. P. van der Zande, B. Naus, L. Smeehuijzen, B. J. Ignacio, K. M. Bonger, J. van den Bossche, S. Kersten, R. Stienstra

The paper introduces CENCAT, a method to measure protein synthesis inhibition in immune cells using noncanonical amino acid tagging, showing its utility in analyzing metabolic responses in complex samples and tissue-resident immune cells.

bioRxiv · Aug 3, 2023 · PreprintImmunology

Caveolae mediated endocytosis of VLDL particles in macrophages requires NPC1 and STARD3 for further lysosomal processing

L. Deng, F. Vrieling, R. Stienstra, G. Hooiveld, A. L. Feitsma, S. Kersten

The paper investigates how macrophages process VLDL-triglycerides, showing caveolae-mediated endocytosis and the roles of LPL, lysosomal acid lipase, Stard3, and NPC1 in lipid uptake, hydrolysis, and efflux.

bioRxiv · Dec 16, 2021 · PreprintCell Biology

Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections

M. T. Heemskerk, C. J. Korbee, J. Esselink, C. Carvalho dos Santos, S. van Veen, I. F. Gordijn, F. Vrieling, K. V. Walburg, C. G. Engele, K. Dijkman, L. Wilson, F. A. Verreck, M. C. Haks, T. H. Ottenhoff

This study identifies two antipsychotic drugs, Pimozide and Fluspirilene, as potential host-directed therapies for Mycobacterium tuberculosis and Salmonella enterica infections by modulating autophagy and lysosomal responses.

bioRxiv · Jun 5, 2021Immunology