Author

F. Xian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

D. Gomez-Varela· 2 shared M. Schmidt· 2 shared A. Metwaly· 1 shared A. Vazquez· 1 shared B. Janji· 1 shared B. Stecher· 1 shared C. Delbrouck· 1 shared C. Jaeger· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

D. Gomez-Varela

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease

E. Urbauer, D. Aguanno, N. Mindermann, H. Omer, A. Metwaly, T. Krammel, T. Faro, M. Remke, S. Reitmeier, S. Bärthel, J. Kersting, Z. Huang, F. Xian, M. Schmidt, D. Saur, , D. Haller

The paper shows mitochondrial dysfunction in intestinal epithelium leads to microbiota-dependent injury and identifies gene signatures that distinguish active from inactive inflammation in IBD.

bioRxiv · Jul 27, 2023 · PreprintMicrobiology

Expanding the Characterization of Microbial Ecosystems using DIA-PASEF Metaproteomics

D. Gomez-Varela, F. Xian, S. Grundtner, J. R. Sondermann, G. Carta, M. Schmidt

This study introduces a DIA-PASEF metaproteomic workflow that enhances protein and taxon identification in mouse gut microbiota and host proteome, revealing more functional pathways and host-microbiome interactions in a chronic pain model.

bioRxiv · Mar 16, 2023 · PreprintMicrobiology

Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis

N. Kiweler, C. Delbrouck, V. I. Pozdeev, L. Neises, L. Soriano-Baguet, K. Eiden, F. Xian, M. Benzarti, L. Haase, E. Koncina, M. Schmoetten, C. Jaeger, M. Z. Noman, A. Vazquez, B. Janji, , J. Meiser

This study identifies mitochondrial one-carbon metabolism as a key driver of cancer cell migration and metastasis independent of proliferation.

Nature Communications · May 16, 2022Peer-reviewedCancer Biology