Author

A. Metwaly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metagenomics· 1 Organism:plant (other)· 1

Frequent Co-Authors

D. Haller· 3 shared K. Steiger· 2 shared M. Allez· 2 shared A. Bleich· 1 shared A. Grodziecki· 1 shared A. Mayorgas· 1 shared A. Salas· 1 shared A. Schnieke· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

D. Haller

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease

E. Urbauer, D. Aguanno, N. Mindermann, H. Omer, A. Metwaly, T. Krammel, T. Faro, M. Remke, S. Reitmeier, S. Bärthel, J. Kersting, Z. Huang, F. Xian, M. Schmidt, D. Saur, , D. Haller

The paper shows mitochondrial dysfunction in intestinal epithelium leads to microbiota-dependent injury and identifies gene signatures that distinguish active from inactive inflammation in IBD.

bioRxiv · Jul 27, 2023 · PreprintMicrobiology

A translational swine model for Crohn`s disease

T. Winogrodzki, A. Metwaly, A. Grodziecki, W. Liang, B. Klinger, K. Flisikowski, T. Flisikowska, K. Fischer, K. Steiger, D. Haller, A. Schnieke

This paper develops a genome-edited swine model of Crohn's disease that replicates key human disease features to enable translational research.

bioRxiv · Jul 8, 2022 · PreprintBioengineering

Diet prevents the expansion of segmented filamentous bacteria and ileo-colonic inflammation in a model of Crohn's disease

A. Metwaly, J. Jovic, N. Waldschmitt, S. Khaloian, H. Heimes, D. Haecker, N. Hammoudi, L. Le Bourhis, A. Mayorgas, K. Siebert, M. Basic, T. Schwerd, M. Allez, J. Panes, A. Salas, , D. Haller

This study shows that diet can prevent ileo-colonic inflammation in a Crohn's disease model by reducing segmented filamentous bacteria (SFB) abundance.

bioRxiv · Jul 6, 2022 · PreprintMicrobiology