Cell BiologybioRxivPreprint
Synergistic effects of deleting the tyrosine phosphatases Shp1 and Shp2 on megakaryopoiesis and thrombopoiesis in mice
Elsa Barré, Marc‐Damien Lourenco‐Rodrigues, Lucie Zimmermann…·Alexandra Mazharian
This study shows that deleting Shp1 and Shp2 in mice impairs megakaryopoiesis and thrombopoiesis, leading to macrothrombocytopenia and reduced platelet function.
DOI 10.1101/2025.10.24.684367