This study identifies 26 risk loci for fibromyalgia through a genome-wide association analysis of 2.5 million individuals, revealing genetic links to neural functions and chronic pain disorders.

Nature Medicine · Jul 28, 2026Peer-reviewedGenetic & Genomic Medicine

Genetic variants affect diurnal glucose levels throughout the day

FinnGen, Estonian Biobank Research Team, VA Million Veteran Program, Nasa Sinnott-Armstrong, Satu J. Strausz, Lea Urpa, Erik Abner, Josephine P. Johnson, Jesse Tyler Valliere, Teele Palumaa, Priit Palta, Hassan S. Dashti, Kyong‐Mi Chang, Marijana Vujković, Mark J. Daly, , Hanna Maria Ollila

The paper identifies genetic variants associated with diurnal glucose levels and their role in type 2 diabetes risk.

Nature Communications · May 22, 2026Peer-reviewedGenetics

From Normal Variation in Sleep to Clinical Sleep Disorders: Genetic Insights from Over One Million Individuals

Lovemore Kunorozva, Jesse Tyler Valliere, Chia‐Yen Chen, Matthew Maher, Cynthia Ines Mantho Tchio, Angus C. Burns, Yingzhe Zhang, Satu J. Strausz, FinnGen, John Weyl Winkelman, Daniel J. Gottlieb, Tian Ge, Andrew R. Wood, Michael N. Weedon, Samuel E. Jones, , Jacqueline M. Lane

This study identifies genetic associations for multiple sleep disorders and medications in over 1.6 million individuals, revealing shared and unique genetic factors across sleep traits.

medRxiv · Nov 21, 2025 · PreprintGenetic & Genomic Medicine

Regulatory variation at serotonin receptor 1F (HTR1F) modulates arousals and risk for sleep apnea

Satu J. Strausz, Martin E. Broberg, Samuel E. Jones, Jukka T. Koskela, Tuomo Kiiskinen, FinnGen, Aarno V. Palotie, Tuula Palotie, Adel Bachour, Richa Saxena, Samuli Ripatti, Erik Abner, Hanna Maria Ollila

The paper identifies regulatory variation at HTR1F associated with sleep apnea risk and arousals, particularly in non-obese individuals.

medRxiv · Aug 29, 2024 · PreprintGenetic & Genomic Medicine

Image-based profiling of healthy donor immune cells with Blood Cell Painting reveals novel genotype-phenotype associations

C. Hogel-Starck, V. A. Timonen, G. Atarsaikhan, I. Mogollon, M. Polso, A. Hassinen, J. Honkanen, C. David Sarmento, J. Koski, J. Soini, L. Urpa, T. Ruokoranta, T. Ahlnas, J. Juvila, J. J. Miettinen, , E. Pitkanen

The paper develops Blood Cell Painting (BCP) to profile immune cell morphology in healthy donors, identifying genetic and clinical associations with immune cell features.

bioRxiv · May 17, 2024 · PreprintCell Biology

SIRPα controls CD47-dependent platelet clearance in mice and humans

M. Shoham, Y. Y. Yiu, P. Hansen, A. Subramaniam, M. Broberg, E. Gars, T. Raveh, FinnGen, I. L. Weissman, N. Sinnott-Armstrong, A. Krishnan, H. Ollila, M. C. Tal

This study shows that the CD47-SIRP axis regulates platelet homeostasis and that blocking this interaction affects platelet levels in mice and humans.

bioRxiv · Dec 9, 2023 · PreprintImmunology

Novel Association of Lyme Disease, Age, and Atopic Dermatitis

B. T. Lee, S. Galloway, Q. Feng, S. Strausz, P. Hansen, L. B. Torrez-Dulgeroff, G. Blacker, Y. Y. Yiu, P. Mansfield, FinnGen, A. Saleem, E. Gars, E. Sanders, I. L. Weissman, H. Ollila, M. C. Tal

This study identifies a novel association between Lyme disease, age, and atopic dermatitis using both murine models and human epidemiological data.

bioRxiv · Jan 27, 2022 · PreprintImmunology

Genome-Wide Polygenic Risk Score Identifies Individuals at Elevated Parkinson's Disease Risk

Yingnan Han, Erin A. Teeple, Srinivas Shankara, Mahdiar Sadeghi, Cheng Zhu, Dongyu Liu, FinnGen, Clarence Wang, Francesca Frau, Katherine Wood Klinger, Stephen L. Madden, Deepak K. Rajpal, S. Pablo Sardi, Dinesh Kumar

This paper computes a genome-wide polygenic risk score for Parkinson's Disease using 6.2 million variants and finds it strongly associates with increased disease risk and earlier onset.

medRxiv · Oct 16, 2020 · PreprintGenetic & Genomic Medicine