Author

Frances Liang

Dana-Farber Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aidan Holmes· 1 shared Audrey E. Van HeestiD· 1 shared Howard Y. ChangiD· 1 shared Itay AlgoviD· 1 shared Liangliang HaoiD· 1 shared Megan HoptoniD· 1 shared Suhas SrinivasaniD· 1 shared Xin X. ZhouiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperBioengineering

Aidan Holmes

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2 papers

Recent·Most cited

BioengineeringNature Chemical BiologyPeer-reviewedMay 11, 2026

A Tissue Proteolysis Activity Mapping and Substrate Discovery Platform for Identifying Novel Tumor-Activated Biosensors

Itay Algov, Audrey E. Van Heest, Megan Hopton…·Xin X. Zhou

This paper introduces PSurf, a platform for identifying tissue-specific protease sensors, and demonstrates its use in detecting tumor-specific proteolytic activity in lung tissue.

3 citationstop 3%

mouseproteomics

𝕏 PostBluesky

BioinformaticsbioRxivPreprintSep 29, 2025

PLI Analyzer for Data-driven Validation of AI Predicted Biomolecular Interfaces

Frances Liang, Suhas Srinivasan, Howard Y. Chang

PLI-Analyzer evaluates AI-predicted biomolecular interfaces by analyzing atomic contacts and domain annotations, revealing discrepancies in predicted protein-protein complexes.

DOI 10.1101/2025.09.29.678845

protein structurestatistical model

𝕏 PostBluesky