Author

Frederique Fallone

Institut de Pharmacologie et Biologie Structurale (IPBS), Universite de Toulouse, Centre National de la Recherche Scientifique, Universite Toulouse III, CNRS, IPBS, Toulouse, France;

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Cell Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:mouse· 1

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Alicia Deleris· 1 shared Anne Gonzalez de PeredoiD· 1 shared Arnaud Metais· 1 shared Baptiste Casel· 1 shared Brigitte Raynaud-Messina· 1 shared Camille GorltiD· 1 shared Christel Verollet· 1 shared Frederic Lagarrigue· 1 shared

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2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alicia Deleris

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintNov 13, 2026

Uncoupling Osteoclast Fusion and Resorptive Activity Through Differential Talin1-Rap1 Signalling Pathways

Marianna Plozza, Rosa Nicole Freiberger, Arnaud Metais…·Frederic Lagarrigue

This study uncovers distinct roles of RIAM and Lpd in osteoclast fusion and resorption through differential Rap1-Talin1 signaling, showing that disrupting the direct Rap1-Talin1 interaction reduces bone resorption and increases bone mass.

DOI 10.64898/2026.11.11.765932

mouseexperimental assay

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