Görkem Garipler

The paper designs stable mRNA 3' UTRs using machine learning and experimental validation, achieving higher protein production in mouse models.

Capybara measures cell identity and fate transitions using a continuum-based approach, showing improved performance in annotating cells and identifying transitions in hematopoiesis and reprogramming.

A CRISPR screen identifies ZBTB11 and ZFP131 as factors maintaining pluripotency by pausing POL II at pro-differentiation genes.

This study shows that reducing glucose or PKA pathway activity improves proliferation of yeast lacking mtDNA and alters gene expression related to amino acid metabolism.