G. A. Bazykin

The paper analyzes mutational signatures in E. coli strains to show DNA polymerase errors, not DNA repair disruptions, drive mutation accumulation in both natural and lab settings.

The paper analyzes longitudinal BCR repertoires to show clonal persistence and differentiation into ASCs with positive selection and affinity maturation.

The paper analyzes genetic variation in Schizophyllum commune, finding that nonsynonymous site linkage disequilibrium suggests positive epistasis and balancing selection.

This paper develops a method to detect changes in amino acid fitness across lineages using phylogenetic and sequence data, validated on HIV-1 and influenza A proteins.

The paper identifies pairs of compensatory frameshifting mutations in vertebrates and insects, showing they generate novel protein sequences and contribute to evolutionary diversity.

This study compares the population genomics of two anhydrobiotic midges, revealing differences in the genetic architecture and adaptation of the PIMT gene family to desiccation.

The paper shows that mRNA editing sites in cephalopods are shaped by adaptive evolution through substitutions that mimic the edited nucleotides, indicating a role for RNA editing in molecular adaptation.

The paper distinguishes between entrenchment and senescence in amino acid site evolution, showing entrenchment dominates in negatively selected sites while senescence occurs in positively selected sites.

The paper measures mutation accumulation in Schizophyllum commune mycelium, finding a high mutation rate per meter of growth compared to other species.

SELVa simulates evolutionary substitution processes under changing fitness landscapes across a phylogeny of lineages.

This study investigates genetic changes in Podospora anserina during adaptation to submerged cultivation, identifying 125 SNVs and 23 indels across eight populations, with evidence of positive selection on genes related to growth and development.

The paper examines parallel adaptation to freshwater in threespine stickleback populations, finding that divergence islands (DIs) are clustered and some are universal across populations.

The paper identifies error-prone bypass of DNA lesions on the lagging strand as a major source of human germline and cancer mutations, supported by mutational asymmetry analysis and experimental validation.

The paper analyzes loss-of-function allele prevalence across 32 metazoan species and finds no correlation with lifetime fecundity or other life-history traits.

The paper detects bursts of rapid amino acid substitutions in proteins across two species groups, attributing them to positive selection rather than neutral processes.

The paper shows that pathogenic amino acid variants in human mitochondrial proteins are more common in closely related species than distant ones, suggesting these variants are more tolerated in humans.