Cell BiologybioRxivPreprint
dsRNA-induced condensation of antiviral proteins promotes PKR activation
G. A. Corbet, J. M. Burke, G. R. Bublitz, R. Parker
The paper shows that dsRNA induces the formation of cytosolic condensates (dRIFs) that enhance PKR activation, leading to translational arrest and stress granule formation.
DOI 10.1101/2022.01.14.476399