Author

G. A. Loset

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Immunology· 1

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

E. S. Vik· 1 shared G. Berntsen· 1 shared I. Hodnebrug· 1 shared I. Sandlie· 1 shared J. J. Gray· 1 shared J. Jahnsen· 1 shared J. R. Jeliazkov· 1 shared K. E. A. Lundin· 1 shared

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2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

E. S. Vik

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1 paper

Recent·Most cited

ImmunologyScience ImmunologyPeer-reviewedAug 10, 2021

Affinity-engineered human antibodies detect celiac disease gluten pMHC complexes and inhibit T-cell activation

R. Frick, L. S. Hoydahl, I. Hodnebrug…·G. A. Loset

The paper describes the engineering of high-affinity human antibodies that recognize gluten epitopes bound to HLA-DQ2.5 and inhibit T-cell activation in celiac disease.

DOI 10.1126/sciimmunol.abg4925

humanproteomics

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