BiochemistrybioRxivPreprint
How Aberrant N-Glycosylation Can Alter Protein Functionality and Ligand Binding: an Atomistic View
M. Castelli, P. Yan, A. Rodina…·G. Colombo
The paper investigates how N-glycosylation of GRP94 modulates its conformational dynamics and ligand binding, providing insights for designing inhibitors targeting disease-associated conformations.
DOI 10.1101/2022.12.22.521543