Cancer BiologybioRxivPreprint
LKB1 regulates JNK-dependent stress signaling and apoptotic dependency of KRAS-mutant lung cancers
C. Li, M. U. Syed, A. Nimbalkar…·A. N. Hata
This study shows LKB1 suppresses JNK-dependent stress signaling in KRAS-mutant lung cancers, revealing a therapy-induced vulnerability that could improve KRAS-targeted therapies.
DOI 10.1101/2022.09.29.510137