Author

G. Houtak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. J. Psaltis· 3 shared G. Bouras· 3 shared G. Shaghayegh· 3 shared P.-J. Wormald· 3 shared R. Nepal· 3 shared S. Vreugde· 3 shared C. Bennett· 1 shared C. Cooksley· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersMicrobiology

A. J. Psaltis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivApr 27, 2023

Prophage acquisition by Staphylococcus aureus contributes to the expansion of Staphylococcal immune evasion

R. Nepal, G. Houtak, G. Bouras…·S. Vreugde

This study shows that acquisition of the {phi}Sa3int prophage by S. aureus alters its exoproteome, enhancing immune evasion and chronic infection potential.

DOI 10.1002/mco2.70313

humanwhole-genome sequencing

𝕏 PostBluesky

ImmunologybioRxivPreprintMar 29, 2023

Staphylococcus aureus biofilm secreted factors cause mucosal damage, mast cell infiltration and goblet cell hyperplasia in a rat rhinosinusitis model

G. Houtak, R. Nepal, G. Bouras…·S. Vreugde

This study shows that S. aureus biofilm secreted factors from CRS patients cause more severe mucosal inflammation in rats compared to controls.

DOI 10.1101/2023.03.29.534842

ratbulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivMar 28, 2023

The Intra-Host Evolutionary Landscape And Pathoadaptation Of Persistent Staphylococcus aureus In Chronic Rhinosinusitis

G. Houtak, G. Bouras, R. Nepal…·S. Vreugde

This study examines S. aureus persistence and pathoadaptation in CRS patients, finding 41% of isolates are persisters with increased biofilm biomass and plasmid copy numbers.

DOI 10.1099/mgen.0.001128

humanwhole-genome sequencing

𝕏 PostBluesky