BiochemistrybioRxivPreprint
Structural and molecular determinants of CCS-mediated copper activation of MEK1/2
M. Grasso, G. J. Bond, Y.-J. Kim…·D. C. Brady
The paper reports the X-ray structure of Cu-MEK1, revealing Cu coordination and CCS-mediated Cu transfer, and identifies molecular mechanisms for Cu-stimulated MEK1 kinase activity.
DOI 10.1101/2020.05.01.072124