G. M. Burslem

The paper develops a method to map unfolded protein responses by tagging endogenous proteins and analyzing their localization and stress responses using single-cell RNA sequencing.

This paper introduces a method to systematically discover effector proteins for induced proximity therapeutics by combining high-throughput endogenous protein tagging with small molecule-based recruitment.

This study shows that chicken Tapasin can stabilize human HLA molecules without co-chaperones and can bind peptides, suggesting its use in engineering MHC-I ligand exchange.

The paper reports the X-ray structure of Cu-MEK1, revealing Cu coordination and CCS-mediated Cu transfer, and identifies molecular mechanisms for Cu-stimulated MEK1 kinase activity.