BiochemistrybioRxiv
A novel redox-active switch in Fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily
S. Shrestha, S. Katiyar, C. E. Sanz-Rodriguez…·N. Kannan
This study identifies redox-sensitive cysteines in Fructosamine-3-kinases (FN3Ks) that regulate their activity and dimerization through disulfide bonds, revealing a novel redox regulatory mechanism in the protein kinase superfamily.
DOI 10.1126/scisignal.aax6313