Author

A. S. Edison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Bioengineering· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Assay:metabolomics· 4 Organism:C. elegans· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:benchmarking· 2 Approach:machine learning (classical)· 2

Frequent Co-Authors

A. M. Morse· 2 shared A. O. Shaver· 2 shared B. M. Garcia· 2 shared F. E. Leach· 2 shared G. J. Gouveia· 2 shared A. Manson· 1 shared A. O. A. Michael· 1 shared B. L. Levine· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

A. M. Morse

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Role of ugt genes in detoxification and glycosylation of 1-hydroxy phenazine (1-HP) in Caenorhabditis elegans

M. Z. Asif, K. A. Nocilla, L. T. Ngo, M. K. Shah, Y. Smadi, Z. A. Hafeez, M. Parnes, A. Manson, J. Glushka, F. E. Leach, A. S. Edison

This study investigates the role of ugt genes in detoxifying 1-hydroxyphenazine (1-HP) in C. elegans, showing that ugt-23 and ugt-49 mutants are more sensitive to 1-HP and produce fewer derivatives.

bioRxiv · Nov 21, 2023 · PreprintBiochemistry

Ion Mobility for Unknown Metabolite Identification: Hope or Hype?

C. K. Asef, M. Rainey, B. M. Garcia, G. J. Gouveia, A. O. Shaver, F. E. Leach, A. M. Morse, A. S. Edison, L. McIntyre, F. Fernandez

This study evaluates the use of ion mobility-mass spectrometry (IM-MS) for identifying unknown metabolites in complex samples, highlighting challenges in data analysis and instrumentation performance.

bioRxiv · Aug 26, 2022 · PreprintBiochemistry

Multi-omics characterization of mesenchymal stem/stromal cells for the identification of putative critical quality attributes

T. S. Maughon, X. Shen, D. Huang, A. O. A. Michael, W. A. Shockey, S. H. Andrews, J. M. McRae, M. O. Platt, F. M. Fernandez, A. S. Edison, S. L. Stice, R. A. Marklein

This paper identifies putative critical quality attributes (CQAs) for mesenchymal stem/stromal cells (MSCs) using multi-omics data and PLSR modeling to predict functional capacity.

bioRxiv · May 10, 2021 · PreprintBioengineering

Predicting T Cell Quality During Manufacturing Through an Artificial Intelligence-based Integrative Multi-Omics Analytical Platform

V. Y. Odeh-Couvertier, N. J. Dwarshuis, M. B. Colonna, B. L. Levine, A. S. Edison, T. Kotanchek, K. Roy, W. Torres-Garcia

The paper develops an AI-based platform to predict T cell quality during manufacturing using multi-omics data and identifies critical process parameters and quality attributes.

bioRxiv · May 5, 2021Bioengineering

Long-Term Metabolomics Reference Material

G. J. Gouveia, A. O. Shaver, B. M. Garcia, A. M. Morse, E. C. Andersen, A. S. Edison, L. M. McIntyre

The paper introduces IBAT, a method to create stable reference materials for metabolomics, and demonstrates its application in E. coli and C. elegans, showing significant variance from pre-analytical steps.

bioRxiv · Mar 24, 2021 · PreprintBiochemistry

Diel Investments in Phytoplankton Metabolite Production Influenced by Associated Heterotrophic Bacteria

M. Uchimiya, W. Schroer, M. Olofsson, A. S. Edison, M. A. Moran

The paper investigates how heterotrophic bacteria influence phytoplankton metabolite production and release over diel cycles, finding that bacterial presence increases specific metabolite accumulation.

bioRxiv · Nov 18, 2020 · PreprintEcology

A novel redox-active switch in Fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily

S. Shrestha, S. Katiyar, C. E. Sanz-Rodriguez, N. R. Kemppinen, H. W. Kim, R. Kadirvelraj, C. Panagos, N. Keyhaninejad, M. Colonna, P. Chopra, D. P. Byrne, G. J. Boons, E. V. Knaap, P. Eyers, A. S. Edison, , N. Kannan

This study identifies redox-sensitive cysteines in Fructosamine-3-kinases (FN3Ks) that regulate their activity and dimerization through disulfide bonds, revealing a novel redox regulatory mechanism in the protein kinase superfamily.

bioRxiv · Jan 13, 2020Biochemistry