Author

G. J. Thomas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:fungi (other)· 1

Frequent Co-Authors

A. Chakravarthy· 1 shared A. Feber· 1 shared A. Furness· 1 shared A. L. Hills· 1 shared C. H. Ottensmeier· 1 shared C. J. Hanley· 1 shared E. Ghorani· 1 shared E. V. King· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. Chakravarthy

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Author profile →

3 papers

Recent·Most cited

Spatially discrete signalling niches regulate fibroblast heterogeneity in human lung cancer

C. J. Hanley, S. Waise, R. Parker, M. A. Lopez, J. Taylor, L. Kimbley, J. West, C. H. Ottensmeier, M. J. Rose-Zerilli, G. J. Thomas

The paper identifies fibroblast subpopulations in lung cancer using single-cell RNA sequencing and shows their spatial distribution and regulation by TGF-β1 and IL-1.

bioRxiv · Jun 8, 2020 · PreprintCancer Biology

Parallel evolution of multiple mechanisms for demethylase inhibitor fungicide resistance in the barley pathogen Pyrenophora teres f. sp. maculata

W. J. Mair, G. J. Thomas, K. Dodhia, A. L. Hills, K. W. Jayasena, S. R. Ellwood, R. P. Oliver, F. J. Lopez-Ruiz

This study identifies multiple independent mechanisms of DMI fungicide resistance in Pyrenophora teres f. sp. maculata, including promoter insertions and amino acid substitutions.

bioRxiv · Oct 16, 2019Plant Biology

Pan-cancer deconvolution of cellular composition identifies molecular correlates of antitumour immunity and checkpoint blockade response

A. Chakravarthy, A. Furness, K. Joshi, E. Ghorani, K. Ford, M. J. Ward, E. V. King, M. Lechner, T. Marafioti, S. Quezada, G. J. Thomas, A. Feber, T. Fenton

This study identifies immune hot and cold tumour subgroups across cancers using DNA methylation-based deconvolution, linking them to immunotherapy response and immune resistance mechanisms.

bioRxiv · Mar 13, 2018Cancer Biology