M. Lechner

Using Unstructured Crowd-sourced Data to Evaluate Urban Tolerance of Terrestrial Native Species within a California Mega-City

The paper evaluates urban tolerance of native species in Los Angeles using crowd-sourced data to identify patterns and inform biodiversity management.

Immune-Epithelial Dynamics and Tissue Remodeling in Chronically Inflamed Nasal Epithelium via Multi-scaled Transcriptomics

This study uses multi-scaled transcriptomics to investigate immune-epithelial dynamics and tissue remodeling in chronic rhinosinusitis, identifying novel cellular interactions and trajectories associated with nasal polyps.

Notch2 signaling guides B cells away from germinal centers towards marginal zone B cell and plasma cell differentiation

The paper shows Notch2 signaling drives B cells from germinal centers to become marginal zone B cells or plasma cells, with mathematical modeling supporting this pathway.

Tol-Pal system and Rgs proteins interact to promote unipolar growth and cell division in Sinorhizobium meliloti

This study identifies and characterizes Rgs proteins and the Tol-Pal system in S. meliloti, showing their roles in unipolar growth and cell division.

Pan-cancer deconvolution of cellular composition identifies molecular correlates of antitumour immunity and checkpoint blockade response

This study identifies immune hot and cold tumour subgroups across cancers using DNA methylation-based deconvolution, linking them to immunotherapy response and immune resistance mechanisms.